Rob Lowe

Paul Turner

Julie Bowen

Peaches O'Dell

Saffron Burrows

Sophia Becker

Jennifer Morrison

Angela Anderson

David Harbour

Stephen Green

Eric McCormack

Larry Becker

Carrie-Anne Moss

Penelope Nelson

Amanda Crew

Helena St. John

Richard Schiff

Dimitris Vargas

Lisa Pepper

Amy

Jenica Bergere

Molly

Chris Mulkey

Roger Fillmore

Brooke Newton

Tawny Shearson

Jamie Chung

Kerstin Rhee

Ella Dershowitz

Ariel Becker

Eddie George

Tony Blanchard

Michelle Krusiec

Shannon Haung

Frankie Shaw

Samantha

Sarah Poynter

Daisy Green

Kurt Yaeger

Oliver Kennedy

Sara Mornell

Janice

Davey Havok

Jimmy McSorley

Brandon Scott

Max

Rosalind Chao

Kate - Focus Group Moderator

Ryan Alosio

Johnny Duncan

David Fine

Tommy

Melissa Stephens

Christina - Kentucky Club Dancer

Elizabeth Wagner

Kentucky Newscaster

Cynthia Popper

Kentucky TV Reporter

Dan Rubin

Skip Richards

Mark Plutynski

Trip Simmons

Tina D'Elia

Boston Waitress

Michael Song

Grocer

Luke Rampersad

Barista

Shirley Manson

Nicole (uncredited)

Deanna Marks

Amy (uncredited)

Jeffrey Moon

Doctor (uncredited)

Maura Mannle

Penelope's Friend (uncredited)

Toni Staniewicz

Penelope's Aide (uncredited)

Jimmy Giliberti

Journalist (uncredited)